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You’ve seen the listicles. “Top 10 Supplements for Energy!” “Best Vitamins for Gut Health!” They’re all opinions dressed up as advice. We built something different.

Every rating on this site comes from a real meta-analysis of randomized controlled trials. That’s the gold standard in medical research. We pool data from multiple studies, calculate actual effect sizes, and tell you what the numbers say. No guessing. No vibes.

You’ll get a clear verdict for each supplement claim. Does it work? Maybe? No evidence at all? We show you the data behind every answer, including forest plots, confidence intervals, and study counts. If you want to dig deeper, you can. If you just want the bottom line, we’ve got that too.

Browse all supplements to see what we’ve rated so far. Or check out how we rate to understand our process from start to finish.

This isn’t another “top 10” site. It’s a reference tool built on published research. We don’t sell supplements. We don’t take money from brands. We just read the studies so you don’t have to.

Supplements We've Rated

Collagen

Joint pain evidence is solid. Skin benefits look good until you remove industry-funded studies. Gut health claims have …

Improves skin elasticity and hydration
Reduces joint pain
Supports gut health
Increases bone mineral density

Creatine

Strong evidence for strength and muscle mass from massive meta-analyses. Emerging evidence for cognition, especially in …

Increases strength and power
Builds muscle mass
Improves cognition
Reduces exercise fatigue

Curcumin

Strong evidence for lowering inflammation markers and relieving joint pain. Comparable to NSAIDs for osteoarthritis with …

Reduces inflammation markers
Relieves joint pain
Improves depression symptoms
Lowers blood sugar and improves glycemic control

Magnesium

Strong evidence for small blood pressure reductions. Modest evidence for sleep. Suggestive for anxiety. Doesn't prevent …

Improves sleep quality
Reduces anxiety
Lowers blood pressure
Prevents muscle cramps

Melatonin

Strong evidence for faster sleep onset and jet lag prevention. Modest evidence for sleep quality. Low doses (0.5-3mg) …

Reduces time to fall asleep
Prevents jet lag
Improves overall sleep quality
Acts as a potent antioxidant

Omega-3 / Fish Oil

Strong evidence for reducing heart disease risk, triglycerides, and inflammation. Moderate evidence for depression, but …

Reduces heart disease risk
Lowers inflammation
Improves depression symptoms
Reduces triglycerides

Probiotics

Strong evidence for IBS symptoms across 72+ RCTs. Proven for AAD and C. difficile prevention. Cochrane-backed for …

Improves IBS and gut health
Reduces respiratory infections
Improves mood and depression
Prevents antibiotic-associated diarrhea

Vitamin D

Strong evidence for immune function, respiratory infections, and fall prevention at 800-1000 IU daily. Daily dosing may …

Strengthens bones and prevents fractures
Boosts immune function
Reduces depression
Improves muscle strength

Zinc

Strong evidence for immune function and shortening colds. Moderate evidence for acne, especially topical. No real …

Boosts immune function and shortens colds
Increases testosterone
Treats acne
Reduces depression symptoms

Ashwagandha

Strong evidence for anxiety and cortisol reduction. Moderate for strength. Weak for testosterone despite marketing …

Reduces anxiety
Lowers cortisol
Increases muscle strength
Boosts testosterone

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